Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
scpBChromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (190 aa)    
Predicted Functional Partners:
scpA
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.999
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.835
Ccel_1743
Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: cth:Cthe_0693 ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.799
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: cth:Cthe_0712 cytidylate kinase.
  
  
 0.730
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
  
  
 0.721
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.721
Ccel_1745
KEGG: cth:Cthe_0690 hypothetical protein.
       0.707
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
    0.662
Ccel_1744
TIGRFAM: sporulation protein YtfJ; PFAM: Sporulation protein YtfJ; KEGG: cth:Cthe_0691 hypothetical protein.
       0.654
Ccel_1748
PFAM: peptidase M50; KEGG: ckl:CKL_2813 protease.
       0.613
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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