Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_1750TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: aoe:Clos_1589 pyrimidine-nucleoside phosphorylase. (440 aa)    
Predicted Functional Partners:
Ccel_0578
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 0.994
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.984
Ccel_1081
PFAM: purine or other phosphorylase family 1; KEGG: cbt:CLH_3244 uridine phosphorylase.
  
 
 0.948
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.947
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
 0.929
Ccel_1435
SMART: AAA ATPase; KEGG: cth:Cthe_0332 phosphoribulokinase/uridine kinase.
    
 0.923
pyrR
Phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.915
Ccel_0909
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: net:Neut_1722 N-isopropylammelide isopropylaminohydrolase.
    
 0.913
Ccel_1174
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: pmy:Pmen_1038 metallophosphoesterase; Belongs to the 5'-nucleotidase family.
    
 0.903
Ccel_1803
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: cth:Cthe_2359 metal dependent phosphohydrolase.
    
  0.903
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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