Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_1776PFAM: Abortive infection protein; KEGG: bay:RBAM_037910 YyaK. (314 aa)    
Predicted Functional Partners:
Ccel_1491
PFAM: type 3a cellulose-binding domain protein; Hyalin; KEGG: LOC587453; similar to hyalin.
  
   
 0.667
addB
ATP-dependent nuclease subunit B; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
       0.662
Ccel_1653
KEGG: cbe:Cbei_2773 hypothetical protein.
  
     0.629
addA
Recombination helicase AddA; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily.
       0.594
Ccel_1562
PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2; KEGG: cac:CAC2325 N-acetylglucosaminidase domain- and ChW repeat-containing cell wall hydrolase.
    
 
 0.537
Ccel_1517
KEGG: sfu:Sfum_1625 hypothetical protein.
  
     0.497
Ccel_1519
KEGG: predicted protein.
  
     0.490
Ccel_1777
PFAM: CoA-binding domain protein; KEGG: cth:Cthe_2077 CoA-binding protein.
       0.489
Ccel_1515
Hypothetical protein; KEGG: bba:Bd2582 cell wall surface anchor family protein.
  
     0.480
Ccel_2442
PFAM: cellulosome protein dockerin type I; KEGG: gvi:gll3705 unknown protein.
  
   
 0.476
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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