Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_1792PFAM: protein of unknown function DUF370; KEGG: cth:Cthe_1316 hypothetical protein; Belongs to the RemA family. (92 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.973
Ccel_1793
PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: cth:Cthe_1317 hypothetical protein.
  
    0.921
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
    0.858
glyQS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.722
Ccel_1120
PFAM: FRG domain protein; KEGG: hne:HNE_3339 hypothetical protein.
  
    0.685
Ccel_0005
KEGG: cth:Cthe_2375 hypothetical protein.
  
   
 0.552
Ccel_1703
PFAM: peptidase S14 ClpP; KEGG: cth:Cthe_1097 ATP-dependent Clp protease proteolytic subunit ClpP.
 
   
 0.430
Ccel_1795
Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.429
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
       0.428
Ccel_1794
PFAM: response regulator receiver; KEGG: cth:Cthe_1318 response regulator receiver protein.
       0.410
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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