Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_1879KEGG: cth:Cthe_1275 H+-ATPase subunit H. (145 aa)    
Predicted Functional Partners:
Ccel_1881
TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: cth:Cthe_1277 putative methyltransferase.
  
    0.837
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.783
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
       0.735
Ccel_0041
PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC.
  
     0.533
rpmB
PFAM: ribosomal protein L28; KEGG: cth:Cthe_1279 50S ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family.
       0.514
Ccel_3329
PFAM: helix-hairpin-helix motif; 8-oxoguanine DNA glycosylase domain protein; SMART: HhH-GPD family protein; KEGG: cth:Cthe_2068 8-oxoguanine DNA glycosylase-like protein.
  
     0.493
Ccel_0534
PFAM: Radical SAM domain protein; KEGG: cth:Cthe_0906 radical SAM family protein.
  
     0.442
Ccel_0170
3D domain protein; PFAM: protein of unknown function DUF348; 3D domain protein; G5 domain protein; KEGG: cth:Cthe_2093 hypothetical protein.
  
     0.404
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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