Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_1889PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: cth:Cthe_1285 metal dependent phosphohydrolase. (487 aa)    
Predicted Functional Partners:
Ccel_1885
KEGG: cth:Cthe_1282 diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GAF domain protein.
 
 0.977
Ccel_2318
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cbe:Cbei_3707 diguanylate cyclase.
 
 0.956
Ccel_0626
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: wsu:WS2095 hypothetical protein.
 
  
 0.872
Ccel_2505
Diguanylate cyclase and metal dependent phosphohydrolase; KEGG: cbe:Cbei_4617 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
 
0.743
glgA-2
Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
  
    0.741
Ccel_2146
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; response regulator receiver; KEGG: cth:Cthe_0725 response regulator receiver modulated metal dependent phosphohydrolase.
  
 
 0.738
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.718
Ccel_1886
PFAM: cell division protein FtsA; KEGG: cno:NT01CX_1629 cell division protein FtsA.
   
 
 0.636
Ccel_0513
PFAM: Patatin; KEGG: cno:NT01CX_0225 patatin-like phospholipase.
   
    0.626
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: tex:Teth514_0255 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.544
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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