STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_1926PFAM: peptidase M18 aminopeptidase I; KEGG: cth:Cthe_0726 putative aminopeptidase 1. (476 aa)    
Predicted Functional Partners:
Ccel_1925
PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2; KEGG: tpd:Teth39_1081 xylose isomerase domain-containing protein.
     
 0.754
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
      0.672
Ccel_1927
TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: cth:Cthe_0724 HisJ family histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
       0.569
Ccel_0499
TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase.
 
     0.523
Ccel_1923
Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: cth:Cthe_0848 peptidase M24; Belongs to the peptidase M24B family.
   
 
 0.481
Ccel_1945
TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; CoA protein activase; KEGG: cth:Cthe_1329 putative CoA-substrate-specific enzyme activase.
       0.459
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.447
aroQ
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.432
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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