STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_1933TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: cth:Cthe_0719 BadM/Rrf2 family transcriptional regulator. (148 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
  
 0.867
Ccel_1931
TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein; KEGG: cth:Cthe_0721 nitrogen-fixing NifU-like protein.
 
  
 0.776
Ccel_1684
PFAM: aminotransferase class V; KEGG: cth:Cthe_1064 aminotransferase, class V.
 
  
 0.692
Ccel_1144
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family.
  
  
 0.668
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.525
Ccel_1934
KEGG: cth:Cthe_0718 hypothetical protein.
       0.470
Ccel_0322
KEGG: cth:Cthe_1768 NifU-like domain-containing protein.
  
  
 0.458
Ccel_2050
TIGRFAM: flagellar motor switch protein FliG; KEGG: cth:Cthe_0466 flagellar motor switch protein G.
   
   0.448
Ccel_1936
PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cth:Cthe_0617 recombination factor protein RarA.
       0.438
Ccel_1634
Molybdopterin oxidoreductase; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: dsy:DSY4615 putative anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.423
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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