Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (171 aa)    
Predicted Functional Partners:
Ccel_0723
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase.
  
 0.963
purH
TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: cth:Cthe_1246 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
  
 0.962
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.927
deoD
TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: cpy:Cphy_0752 purine nucleoside phosphorylase.
    
 0.917
Ccel_1174
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: pmy:Pmen_1038 metallophosphoesterase; Belongs to the 5'-nucleotidase family.
    
 0.905
Ccel_2519
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: afl:Aflv_2607 protein UshA precursor (two S-layer domains; UDP-sugar hydrolase; 5'-nucleotidase); Belongs to the 5'-nucleotidase family.
    
 0.905
Ccel_0607
PFAM: protein of unknown function DUF152; KEGG: cth:Cthe_0911 hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.903
Ccel_3086
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: cth:Cthe_2656 MazG family protein.
    
  0.902
Ccel_0414
PFAM: phosphoribosyltransferase; KEGG: ypg:YpAngola_A4140 putative phosphoribosyl transferase protein.
     
  0.900
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
   
 
 0.814
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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