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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gprSpore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (335 aa)    
Predicted Functional Partners:
Ccel_2281
TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: cth:Cthe_0123 stage V sporulation protein AD.
  
  
 0.916
Ccel_2282
TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: cth:Cthe_0122 SpoVA protein.
  
  
 0.872
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.832
Ccel_3360
TIGRFAM: sporulation protein YyaC; PFAM: protein of unknown function DUF1256; KEGG: cth:Cthe_2165 hypothetical protein.
  
  
 0.821
Ccel_1894
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.811
Ccel_1895
KEGG: cth:Cthe_0813 SpoIVB peptidase; TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; SMART: PDZ/DHR/GLGF domain protein.
  
    0.809
Ccel_1944
TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: cth:Cthe_1328 stage II sporulation P.
 
  
 0.798
Ccel_3088
TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cth:Cthe_2655 AbrB family transcriptional regulator.
  
  
 0.791
Ccel_1561
PFAM: small acid-soluble spore protein alpha/beta type; KEGG: ckl:CKL_3529 small acid-soluble spore protein.
  
  
 0.787
Ccel_2280
TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; KEGG: cth:Cthe_0124 SpoVA protein.
  
  
 0.783
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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