node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccel_1144 | Ccel_1992 | Ccel_1144 | Ccel_1992 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | 0.495 |
Ccel_1144 | guaA | Ccel_1144 | Ccel_2202 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.672 |
Ccel_1144 | thiE | Ccel_1144 | Ccel_1989 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.661 |
Ccel_1144 | truA | Ccel_1144 | Ccel_0793 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.753 |
Ccel_1988 | Ccel_1992 | Ccel_1988 | Ccel_1992 | PFAM: glycosyl transferase family 2; chitin synthase; KEGG: cpo:COPRO5265_0045 chitin synthase. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | 0.439 |
Ccel_1988 | thiC | Ccel_1988 | Ccel_1991 | PFAM: glycosyl transferase family 2; chitin synthase; KEGG: cpo:COPRO5265_0045 chitin synthase. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.437 |
Ccel_1988 | thiE | Ccel_1988 | Ccel_1989 | PFAM: glycosyl transferase family 2; chitin synthase; KEGG: cpo:COPRO5265_0045 chitin synthase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.474 |
Ccel_1988 | thiM | Ccel_1988 | Ccel_1990 | PFAM: glycosyl transferase family 2; chitin synthase; KEGG: cpo:COPRO5265_0045 chitin synthase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.453 |
Ccel_1992 | Ccel_1144 | Ccel_1992 | Ccel_1144 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family. | 0.495 |
Ccel_1992 | Ccel_1988 | Ccel_1992 | Ccel_1988 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | PFAM: glycosyl transferase family 2; chitin synthase; KEGG: cpo:COPRO5265_0045 chitin synthase. | 0.439 |
Ccel_1992 | Ccel_2006 | Ccel_1992 | Ccel_2006 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.623 |
Ccel_1992 | Ccel_2120 | Ccel_1992 | Ccel_2120 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | TIGRFAM: proton-coupled thiamine transporter YuaJ; PFAM: thiamine transporter YuaJ; KEGG: chy:CHY_0230 proton-coupled thiamine transporter YuaJ. | 0.515 |
Ccel_1992 | Ccel_3104 | Ccel_1992 | Ccel_3104 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cbe:Cbei_4439 thiamine biosynthesis protein ThiH. | 0.498 |
Ccel_1992 | guaA | Ccel_1992 | Ccel_2202 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.558 |
Ccel_1992 | thiC | Ccel_1992 | Ccel_1991 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.997 |
Ccel_1992 | thiE | Ccel_1992 | Ccel_1989 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
Ccel_1992 | thiM | Ccel_1992 | Ccel_1990 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.998 |
Ccel_1992 | truA | Ccel_1992 | Ccel_0793 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.544 |
Ccel_2006 | Ccel_1992 | Ccel_2006 | Ccel_1992 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cbf:CLI_0857 phosphomethylpyrimidine kinase. | 0.623 |
Ccel_2006 | guaA | Ccel_2006 | Ccel_2202 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.799 |