| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccel_0016 | Ccel_1164 | Ccel_0016 | Ccel_1164 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase. | 0.999 |
| Ccel_0016 | Ccel_2018 | Ccel_0016 | Ccel_2018 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | KEGG: cth:Cthe_0501 hypothetical protein. | 0.454 |
| Ccel_0016 | Ccel_2021 | Ccel_0016 | Ccel_2021 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | PFAM: protein of unknown function DUF342; KEGG: cth:Cthe_0498 hypothetical protein. | 0.467 |
| Ccel_0016 | aroE | Ccel_0016 | Ccel_0663 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.518 |
| Ccel_0478 | Ccel_2006 | Ccel_0478 | Ccel_2006 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.481 |
| Ccel_0478 | Ccel_2018 | Ccel_0478 | Ccel_2018 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | KEGG: cth:Cthe_0501 hypothetical protein. | 0.428 |
| Ccel_1164 | Ccel_0016 | Ccel_1164 | Ccel_0016 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.999 |
| Ccel_1164 | Ccel_2018 | Ccel_1164 | Ccel_2018 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase. | KEGG: cth:Cthe_0501 hypothetical protein. | 0.453 |
| Ccel_1164 | aroE | Ccel_1164 | Ccel_0663 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.438 |
| Ccel_2006 | Ccel_0478 | Ccel_2006 | Ccel_0478 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | 0.481 |
| Ccel_2006 | Ccel_2018 | Ccel_2006 | Ccel_2018 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: cth:Cthe_0501 hypothetical protein. | 0.416 |
| Ccel_2006 | aroE | Ccel_2006 | Ccel_0663 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.461 |
| Ccel_2018 | Ccel_0016 | Ccel_2018 | Ccel_0016 | KEGG: cth:Cthe_0501 hypothetical protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.454 |
| Ccel_2018 | Ccel_0478 | Ccel_2018 | Ccel_0478 | KEGG: cth:Cthe_0501 hypothetical protein. | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | 0.428 |
| Ccel_2018 | Ccel_1164 | Ccel_2018 | Ccel_1164 | KEGG: cth:Cthe_0501 hypothetical protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase. | 0.453 |
| Ccel_2018 | Ccel_2006 | Ccel_2018 | Ccel_2006 | KEGG: cth:Cthe_0501 hypothetical protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.416 |
| Ccel_2018 | Ccel_2019 | Ccel_2018 | Ccel_2019 | KEGG: cth:Cthe_0501 hypothetical protein. | KEGG: cth:Cthe_0500 hypothetical protein. | 0.655 |
| Ccel_2018 | Ccel_2020 | Ccel_2018 | Ccel_2020 | KEGG: cth:Cthe_0501 hypothetical protein. | KEGG: cth:Cthe_0499 hypothetical protein. | 0.557 |
| Ccel_2018 | Ccel_2021 | Ccel_2018 | Ccel_2021 | KEGG: cth:Cthe_0501 hypothetical protein. | PFAM: protein of unknown function DUF342; KEGG: cth:Cthe_0498 hypothetical protein. | 0.465 |
| Ccel_2018 | Ccel_2022 | Ccel_2018 | Ccel_2022 | KEGG: cth:Cthe_0501 hypothetical protein. | TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cth:Cthe_0495 RNA polymerase, sigma 28 subunit. | 0.520 |