Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2060TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain protein; KEGG: cth:Cthe_0449 hypothetical protein. (86 aa)    
Predicted Functional Partners:
Ccel_2061
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.904
Ccel_2062
RNA polymerase, sigma 28 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.869
Ccel_2063
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
 
   
 0.821
Ccel_0292
TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R; KEGG: cth:Cthe_1920 stage II sporulation protein R.
 
     0.795
Ccel_1703
PFAM: peptidase S14 ClpP; KEGG: cth:Cthe_1097 ATP-dependent Clp protease proteolytic subunit ClpP.
 
   
 0.784
Ccel_2282
TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: cth:Cthe_0122 SpoVA protein.
  
    0.783
Ccel_0521
PFAM: GerA spore germination protein; KEGG: cth:Cthe_0667 GerA spore germination protein.
  
    0.764
Ccel_1913
TIGRFAM: stage III sporulation protein AD; PFAM: Sporulation stage III protein AD; KEGG: cth:Cthe_0842 stage III sporulation protein AD.
  
     0.764
Ccel_1916
TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: cth:Cthe_0845 stage III sporulation protein spoIIIAA.
  
    0.760
Ccel_1895
KEGG: cth:Cthe_0813 SpoIVB peptidase; TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; SMART: PDZ/DHR/GLGF domain protein.
  
     0.755
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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