STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_2076KEGG: cth:Cthe_0889 putative transmembrane anti-sigma factor. (384 aa)    
Predicted Functional Partners:
Ccel_2077
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cth:Cthe_0890 ECF subfamily RNA polymerase sigma-24 factor.
  
 
 0.860
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.787
Ccel_2073
PFAM: Lytic transglycosylase catalytic; KEGG: cpr:CPR_1960 secreted protein.
 
     0.781
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.774
Ccel_1735
KEGG: cth:Cthe_0704 hypothetical protein.
  
     0.772
Ccel_0097
KEGG: cth:Cthe_2241 hypothetical protein.
  
     0.683
Ccel_0301
KEGG: cth:Cthe_2712 hypothetical protein.
  
    0.680
Ccel_1315
PFAM: type IV pilus assembly PilZ; KEGG: cth:Cthe_0488 type IV pilus assembly PilZ.
  
     0.680
Ccel_0107
PFAM: FlgN family protein; KEGG: cth:Cthe_2216 hypothetical protein.
  
     0.638
Ccel_0092
PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: cth:Cthe_2246 anti-sigma-28 factor, FlgM.
  
     0.617
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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