Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_2086PFAM: sodium/calcium exchanger membrane region; KEGG: cth:Cthe_3173 sodium/calcium exchanger membrane region. (335 aa)    
Predicted Functional Partners:
Ccel_2085
KEGG: cth:Cthe_3174 hypothetical protein.
  
    0.560
Ccel_1731
KEGG: cth:Cthe_0710 hypothetical protein.
  
     0.559
Ccel_1698
KEGG: cth:Cthe_0778 hypothetical protein; Belongs to the UPF0342 family.
 
     0.441
Ccel_2238
PFAM: protein of unknown function DUF1292; KEGG: cth:Cthe_0154 hypothetical protein.
  
     0.432
Ccel_2087
PFAM: major facilitator superfamily MFS_1; KEGG: cpy:Cphy_1907 major facilitator transporter.
       0.420
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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