Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_2092PFAM: adenylate cyclase; KEGG: cth:Cthe_2577 adenylate cyclase. (154 aa)    
Predicted Functional Partners:
Ccel_0702
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: dsy:DSY0397 anaerobic ribonucleoside triphosphate reductase.
     
  0.900
Ccel_1831
PFAM: RelA/SpoT domain protein; KEGG: esi:Exig_1629 RelA/SpoT domain-containing protein.
     
  0.900
Ccel_1951
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
Ccel_3086
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: cth:Cthe_2656 MazG family protein.
     
  0.900
Ccel_3227
PFAM: RelA/SpoT domain protein; KEGG: cbe:Cbei_2333 RelA/SpoT domain protein.
     
  0.900
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.801
folE
PFAM: GTP cyclohydrolase I; KEGG: cbb:CLD_2996 GTP cyclohydrolase I.
     
  0.800
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.800
Ccel_2091
PFAM: protein of unknown function UPF0153; KEGG: mms:mma_2931 hypothetical protein.
       0.685
Ccel_2090
PFAM: ThiJ/PfpI domain protein; KEGG: cbe:Cbei_3829 ThiJ/PfpI domain protein.
       0.672
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.