Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_2099PFAM: CheW domain protein; KEGG: tpd:Teth39_1010 CheW protein. (139 aa)    
Predicted Functional Partners:
Ccel_2027
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: cth:Cthe_0490 CheA signal transduction histidine kinases.
 
 0.991
Ccel_2315
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: cbe:Cbei_4829 CheA signal transduction histidine kinase.
 
 0.991
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.969
Ccel_2310
PFAM: CheB methylesterase; KEGG: ckl:CKL_0573 CheB1.
 
 
 0.969
Ccel_0221
PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; CHASE3 domain protein; KEGG: lsp:Bsph_4425 methyl-accepting chemotaxis protein McpA (H1).
 
 0.964
Ccel_0049
PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: dsy:DSY4790 hypothetical protein.
 
 0.955
Ccel_0219
PFAM: chemotaxis sensory transducer; KEGG: cth:Cthe_0266 methyl-accepting chemotaxis sensory transducer.
 
 0.954
Ccel_0493
PFAM: chemotaxis sensory transducer; KEGG: lsp:Bsph_3073 hypothetical protein.
 
 0.954
Ccel_2179
PFAM: chemotaxis sensory transducer; KEGG: cth:Cthe_3156 methyl-accepting chemotaxis sensory transducer.
 
 0.954
Ccel_2636
PFAM: chemotaxis sensory transducer; KEGG: cth:Cthe_0266 methyl-accepting chemotaxis sensory transducer.
 
 0.954
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.