Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2146Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; response regulator receiver; KEGG: cth:Cthe_0725 response regulator receiver modulated metal dependent phosphohydrolase. (206 aa)    
Predicted Functional Partners:
Ccel_2145
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: cth:Cthe_2944 periplasmic sensor signal transduction histidine kinase.
 
 
 0.934
Ccel_1889
PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: cth:Cthe_1285 metal dependent phosphohydrolase.
  
 
 0.738
Ccel_2304
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: aoe:Clos_0989 NADH dehydrogenase (quinone).
   
 
 0.604
Ccel_2144
PFAM: Fascin family protein; KEGG: fscn1l; fascin homolog 1-like, actin-bundling protein (Strongylocentrotus purpuratus).
       0.576
Ccel_0361
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: afl:Aflv_2620 sporulation histidine kinase A.
  
 
 0.569
Ccel_1154
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: cbl:CLK_0191 sensor histidine kinase.
  
 
 0.569
Ccel_3393
PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: cth:Cthe_2332 multi-sensor signal transduction histidine kinase.
 
 
 0.551
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.550
Ccel_2321
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: cbk:CLL_A1409 two component sensor kinase.
  
 
 0.524
Ccel_1419
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mta:Moth_2263 metal dependent phosphohydrolase.
 
      0.521
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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