Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2198Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: plu:plu4700 zinc-responsive transcriptional regulator. (134 aa)    
Predicted Functional Partners:
Ccel_3338
PFAM: regulatory protein MerR; KEGG: cbe:Cbei_0557 putative transcriptional regulator, MerR family.
  
   
 0.698
Ccel_2197
KEGG: cdf:CD0474 putative iron-sulfur protein.
     
 0.589
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.539
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.527
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.482
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.469
Ccel_2199
PFAM: Integrase catalytic region; KEGG: afl:Aflv_2378 transposase.
       0.467
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.466
Ccel_3233
PFAM: Isoprenylcysteine carboxyl methyltransferase; KEGG: ckl:CKL_0584 hypothetical protein.
 
     0.436
Ccel_0252
PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: cth:Cthe_2870 hypothetical protein.
  
    0.404
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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