STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_2246PFAM: protein of unknown function DUF523; KEGG: ckl:CKL_3182 hypothetical protein. (150 aa)    
Predicted Functional Partners:
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
 
     0.800
ddl
D-alanine/D-alanine ligase; Cell wall formation.
 
    0.681
Ccel_1332
TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: cno:NT01CX_0374 bifunctional folate synthesis protein.
 
      0.677
Ccel_2249
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ctc:CTC01951 alkaline phosphatase synthesis sensor protein PhoR.
       0.499
Ccel_2248
KEGG: ctc:CTC01950 hypothetical protein.
       0.498
Ccel_2250
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbf:CLI_0424 DNA-binding response regulator.
       0.498
Ccel_2251
PFAM: polysaccharide deacetylase; KEGG: cpy:Cphy_3069 polysaccharide deacetylase.
       0.477
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: cbb:CLD_1411 phenylalanyl-tRNA synthetase, beta subunit.
       0.418
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: medium (50%) [HD]