Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2249Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ctc:CTC01951 alkaline phosphatase synthesis sensor protein PhoR. (463 aa)    
Predicted Functional Partners:
Ccel_2250
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbf:CLI_0424 DNA-binding response regulator.
 
 
 0.958
Ccel_2248
KEGG: ctc:CTC01950 hypothetical protein.
 
     0.942
Ccel_2106
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cth:Cthe_1394 two component transcriptional regulator.
 
 
 0.741
Ccel_2251
PFAM: polysaccharide deacetylase; KEGG: cpy:Cphy_3069 polysaccharide deacetylase.
       0.737
Ccel_1157
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ckl:CKL_0966 transcriptional regulator.
 
 
 0.732
Ccel_0916
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ckl:CKL_1682 transcriptional regulator.
 
 
 0.726
Ccel_1714
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cth:Cthe_1847 two component transcriptional regulator.
 
 0.717
Ccel_1658
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: dsy:DSY1198 hypothetical protein.
 
 
 0.687
Ccel_2324
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbk:CLL_A1406 regulatory protein VanR.
 
 
 0.680
Ccel_2658
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbk:CLL_A1387 regulatory protein VanR.
 
 
 0.676
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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