Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Ccel_2289Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (434 aa)    
Predicted Functional Partners:
Ccel_2290
Conserved hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.978
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
 
  
 0.931
Ccel_2288
TIGRFAM: glycogen debranching enzyme; PFAM: Amylo-alpha-16-glucosidase; KEGG: cth:Cthe_0115 glycogen debranching enzyme, putative.
 
     0.820
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
       0.760
Ccel_2292
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cth:Cthe_0111 putative hydrolase.
       0.760
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
       0.668
Ccel_0666
TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: cth:Cthe_0727 cell envelope-related transcriptional attenuator.
  
     0.573
Ccel_2286
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cth:Cthe_0118 anti-sigma-factor antagonist.
       0.572
Ccel_1717
TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: cth:Cthe_0727 cell envelope-related transcriptional attenuator.
  
     0.533
Ccel_3093
UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
   
 0.491
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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