STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_2290Conserved hypothetical protein; Displays ATPase and GTPase activities. (291 aa)    
Predicted Functional Partners:
Ccel_2289
Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
  
  
 0.962
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
 
  
 0.906
Ccel_2288
TIGRFAM: glycogen debranching enzyme; PFAM: Amylo-alpha-16-glucosidase; KEGG: cth:Cthe_0115 glycogen debranching enzyme, putative.
       0.803
Ccel_1319
TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; ribonuclease E and G; KEGG: cth:Cthe_0158 ribonuclease G.
 
 
 
 0.801
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
     
 0.798
Ccel_2292
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cth:Cthe_0111 putative hydrolase.
       0.758
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
     
 0.694
Ccel_2286
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cth:Cthe_0118 anti-sigma-factor antagonist.
       0.576
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
 
  
 0.566
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
   
 0.507
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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