Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2318TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cbe:Cbei_3707 diguanylate cyclase. (363 aa)    
Predicted Functional Partners:
Ccel_1889
PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: cth:Cthe_1285 metal dependent phosphohydrolase.
 
 0.956
Ccel_0497
Metal dependent phosphohydrolase; KEGG: cac:CAC3650 HD-GYP domain-containing protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
 0.955
Ccel_3394
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cth:Cthe_2333 two component transcriptional regulator.
 
 
  
 0.897
Ccel_1419
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mta:Moth_2263 metal dependent phosphohydrolase.
 
 
 0.818
Ccel_0194
KEGG: cpo:COPRO5265_1350 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
 0.680
Ccel_0626
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: wsu:WS2095 hypothetical protein.
 
 
0.529
Ccel_2317
PFAM: type IV pilus assembly PilZ; KEGG: cth:Cthe_1173 type IV pilus assembly PilZ.
       0.497
Ccel_0399
KEGG: cth:Cthe_2899 putative anti-sigma regulatory factor, serine/threonine protein kinase.
   
 
 0.459
Ccel_0401
KEGG: cth:Cthe_2901 putative anti-sigma regulatory factor, serine/threonine protein kinase.
   
 
 0.459
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
   
 
 0.459
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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