Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2344PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: cpy:Cphy_0123 FMN-dependent alpha-hydroxy acid dehydrogenase. (300 aa)    
Predicted Functional Partners:
Ccel_1757
L-lactate permease, putative; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.684
Ccel_2343
PFAM: beta-lactamase; KEGG: bcy:Bcer98_1900 beta-lactamase.
       0.645
Ccel_2342
PFAM: ABC transporter related; KEGG: cdf:CD3195 putative excinuclease ABC subunit A.
       0.642
Ccel_2448
PFAM: Rieske [2Fe-2S] domain protein; FAD dependent oxidoreductase; KEGG: nth:Nther_0727 FAD dependent oxidoreductase.
 
 
 0.583
Ccel_1188
PFAM: aminotransferase class V; KEGG: csc:Csac_1303 aminotransferase, class V.
  
 0.552
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.539
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
  
 0.475
tpiA
Phosphoglycerate kinase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.441
Ccel_2341
KEGG: cbf:CLI_2416 hypothetical protein.
       0.424
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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