Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2416TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: cth:Cthe_3108 phage SPO1 DNA polymerase-related protein. (190 aa)    
Predicted Functional Partners:
Ccel_2415
PFAM: Uracil-DNA glycosylase superfamily; KEGG: cth:Cthe_3109 uracil-DNA glycosylase superfamily protein.
 
  
 
0.982
Ccel_3230
PFAM: Uracil-DNA glycosylase superfamily; KEGG: dsy:DSY3733 hypothetical protein.
  
  
 
0.920
Ccel_0800
PFAM: peptidase M22 glycoprotease; KEGG: cth:Cthe_1775 peptidase M22, glycoprotease.
  
    0.445
Ccel_2417
PFAM: glycosyl transferase family 39; KEGG: cth:Cthe_3095 glycosyl transferase family protein.
       0.445
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
    0.416
Ccel_1736
Conserved carboxylase region; PFAM: pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: cth:Cthe_0701 oxaloacetate decarboxylase.
   
    0.413
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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