Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_2473PFAM: dihydropteroate synthase DHPS; KEGG: mta:Moth_1207 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase. (261 aa)    
Predicted Functional Partners:
Ccel_2474
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: ckl:CKL_1762 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
 
  
 0.996
Ccel_1861
PFAM: homocysteine S-methyltransferase; KEGG: tex:Teth514_1211 homocysteine S-methyltransferase.
  
 0.985
Ccel_3199
PFAM: Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: csc:Csac_0423 cobalamin B12-binding domain-containing protein.
  
 0.979
fhs
PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: cth:Cthe_2399 formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.945
Ccel_3201
PFAM: ferredoxin; KEGG: tte:TTE1028 hypothetical protein.
 
 
 
 0.607
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
  
 0.591
Ccel_2475
KEGG: amt:Amet_0741 hypothetical protein.
       0.535
Ccel_2472
PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_1232 AMP-dependent synthetase and ligase.
  
    0.531
Ccel_2471
PFAM: inositol monophosphatase; KEGG: nis:NIS_1712 inositol-phosphate phosphatase.
       0.527
Ccel_1164
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase.
     
 0.514
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.