Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2477PFAM: cell cycle protein; KEGG: cac:CAC0505 cell division membrane protein; Belongs to the SEDS family. (399 aa)    
Predicted Functional Partners:
Ccel_2476
PFAM: penicillin-binding protein transpeptidase; KEGG: cac:CAC0506 penicillin-binding protein.
 
 0.996
Ccel_0474
TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: cth:Cthe_0983 cell cycle protein; Belongs to the SEDS family.
  
  
 
0.920
Ccel_0482
TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family.
  
  
 
0.920
Ccel_2478
PFAM: Forkhead-associated protein; KEGG: cbf:CLI_3569 FHA domain-containing protein.
 
   
 0.883
Ccel_0478
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase.
 
 
 0.836
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.830
Ccel_2067
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 0.812
Ccel_2560
TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cth:Cthe_0091 peptidoglycan glycosyltransferase.
 
 
 0.762
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.730
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.727
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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