Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2479PFAM: protein of unknown function DUF1294; KEGG: cth:Cthe_0204 hypothetical protein. (88 aa)    
Predicted Functional Partners:
Ccel_2480
TIGRFAM: stage V sporulation protein B; PFAM: multi antimicrobial extrusion protein MatE; polysaccharide biosynthesis protein; virulence factor MVIN family protein; KEGG: ctc:CTC00988 stage V sporulation protein B.
       0.486
Ccel_2478
PFAM: Forkhead-associated protein; KEGG: cbf:CLI_3569 FHA domain-containing protein.
       0.437
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
 
     0.430
Ccel_2477
PFAM: cell cycle protein; KEGG: cac:CAC0505 cell division membrane protein; Belongs to the SEDS family.
  
    0.403
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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