Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Ccel_2487TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; KEGG: cac:CAC1625 phosphoserine phosphatase family protein. (219 aa)    
Predicted Functional Partners:
Ccel_2486
3-dehydroquinate synthase; PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: cbe:Cbei_4092 3-dehydroquinate synthase.
 
    0.850
Ccel_2474
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: ckl:CKL_1762 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
   
    0.715
Ccel_1290
PFAM: class II aldolase/adducin family protein; KEGG: cpy:Cphy_1177 class II aldolase/adducin family protein.
  
  
 0.578
Ccel_3467
TIGRFAM: L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein; KEGG: cbt:CLH_3015 L-ribulose-5-phosphate 4-epimerase.
  
  
 0.578
Ccel_0239
Hypothetical protein; KEGG: LOC100083241; similar to vitellogenin.
  
     0.557
Ccel_1718
PFAM: copper amine oxidase domain protein; KEGG: cpo:COPRO5265_1378 putative branched chain amino acid ABC transporter substrate-binding protein.
  
     0.530
Ccel_2488
PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cno:NT01CX_0997 ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
       0.499
mtnK
5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
  
  
 0.471
Ccel_2442
PFAM: cellulosome protein dockerin type I; KEGG: gvi:gll3705 unknown protein.
  
     0.469
Ccel_0804
KEGG: cth:Cthe_2732 hypothetical protein.
  
     0.462
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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