Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2545TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. (464 aa)    
Predicted Functional Partners:
Ccel_2546
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: cth:Cthe_0373 ferredoxin--NADP(+) reductase subunit alpha.
 
 
 0.998
Ccel_2233
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cth:Cthe_0341 NADH dehydrogenase (quinone).
 
 
 0.990
Ccel_2304
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: aoe:Clos_0989 NADH dehydrogenase (quinone).
 
 
 0.987
pyrK
Oxidoreductase FAD/NAD(P)-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 
 0.985
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.965
Ccel_2430
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.942
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.919
Ccel_0561
PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region.
    
 0.914
Ccel_1721
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: cdf:CD0487 putative carbon-nitrogen hydrolase.
  
 0.913
Ccel_1965
PFAM: aminotransferase class I and II; KEGG: cno:NT01CX_0284 aspartate aminotransferase.
  
 
 0.913
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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