Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2558TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: cth:Cthe_0093 septum site-determining protein MinD. (266 aa)    
Predicted Functional Partners:
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
 
 0.997
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
 
 0.991
Ccel_2562
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
    0.873
Ccel_2561
TIGRFAM: rod shape-determining protein MreD; KEGG: cth:Cthe_0090 hypothetical protein.
  
  
 0.787
Ccel_2556
PFAM: MGS domain protein; KEGG: cth:Cthe_0095 methylglyoxal synthase.
  
    0.710
Ccel_2563
TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell division protein FtsA; cell shape determining protein MreB/Mrl; KEGG: cth:Cthe_0088 rod shape-determining protein MreB.
  
 
 0.581
Ccel_2560
TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cth:Cthe_0091 peptidoglycan glycosyltransferase.
     
 0.526
Ccel_2564
PFAM: helix-hairpin-helix motif; DNA repair protein RadC; KEGG: aoe:Clos_1766 DNA repair protein RadC; Belongs to the UPF0758 family.
  
    0.447
Ccel_2554
KEGG: mat:MARTH_orf139 hypothetical protein.
       0.437
Ccel_3102
TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; KEGG: cth:Cthe_2619 rod shape-determining protein MreB.
  
 
 0.432
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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