Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Ccel_2563TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell division protein FtsA; cell shape determining protein MreB/Mrl; KEGG: cth:Cthe_0088 rod shape-determining protein MreB. (340 aa)    
Predicted Functional Partners:
Ccel_2562
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.983
Ccel_2560
TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cth:Cthe_0091 peptidoglycan glycosyltransferase.
 
 
 
 0.908
Ccel_2561
TIGRFAM: rod shape-determining protein MreD; KEGG: cth:Cthe_0090 hypothetical protein.
  
  
 0.789
Ccel_2564
PFAM: helix-hairpin-helix motif; DNA repair protein RadC; KEGG: aoe:Clos_1766 DNA repair protein RadC; Belongs to the UPF0758 family.
  
  
 0.773
Ccel_0474
TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: cth:Cthe_0983 cell cycle protein; Belongs to the SEDS family.
 
 
 0.770
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.686
Ccel_2934
PFAM: cell cycle protein; KEGG: aoe:Clos_2351 cell division membrane protein-like protein; Belongs to the SEDS family.
 
 
 0.686
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.683
Ccel_1486
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cth:Cthe_1011 peptidoglycan glycosyltransferase.
 
 
 
 0.610
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
   0.584
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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