Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2571PFAM: Citrate synthase; KEGG: mta:Moth_1122 methylcitrate synthase; Belongs to the citrate synthase family. (450 aa)    
Predicted Functional Partners:
Ccel_2176
TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: cth:Cthe_3158 aconitate hydratase.
 
 0.991
Ccel_0016
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
    
 0.956
Ccel_1164
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase.
    
 0.945
Ccel_0494
PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_0551 AMP-dependent synthetase and ligase.
  
 0.943
Ccel_1469
PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_0551 AMP-dependent synthetase and ligase.
  
 0.943
Ccel_2576
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: ckl:CKL_0546 isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.935
Ccel_2137
TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; KEGG: cth:Cthe_1029 phosphotransacetylase.
  
 
 0.929
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.916
Ccel_0932
PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: mja:MJ1229 pyruvate carboxylase subunit A.
  
 
 0.914
Ccel_2177
PFAM: pyruvate carboxyltransferase; KEGG: cth:Cthe_3157 pyruvate carboxyltransferase.
  
 
 0.913
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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