Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Ccel_2580KEGG: cpy:Cphy_1044 hypothetical protein. (60 aa)    
Predicted Functional Partners:
Ccel_1448
KEGG: cth:Cthe_1383 tetratricopeptide TPR_2.
  
     0.696
Ccel_2579
PFAM: thioesterase superfamily protein; KEGG: cbe:Cbei_2899 thioesterase superfamily protein.
       0.550
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
     0.539
Ccel_2245
KEGG: cth:Cthe_0149 HPrNtr domain-containing protein.
  
     0.515
Ccel_3004
PFAM: Protein of unknown function DUF1980; KEGG: dsy:DSY0109 hypothetical protein.
  
     0.507
Ccel_0817
PFAM: protein of unknown function DUF402; KEGG: cth:Cthe_2746 hypothetical protein.
  
     0.483
Ccel_2561
TIGRFAM: rod shape-determining protein MreD; KEGG: cth:Cthe_0090 hypothetical protein.
  
     0.436
Ccel_2566
PFAM: Negative regulator of genetic competence; KEGG: cth:Cthe_0085 negative regulator of genetic competence.
  
     0.423
Ccel_0239
Hypothetical protein; KEGG: LOC100083241; similar to vitellogenin.
  
     0.422
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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