STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_2881Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: cth:Cthe_1796 prephenate dehydrogenase. (366 aa)    
Predicted Functional Partners:
Ccel_1618
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Chorismate mutase; DAHP synthetase I/KDSA; KEGG: lin:lin1641 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase.
 0.986
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class V; aminotransferase class I and II; KEGG: cth:Cthe_2883 histidinol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.966
pheA
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cth:Cthe_2260 prephenate dehydratase.
 
 0.963
Ccel_1042
PFAM: aminotransferase class I and II; KEGG: cdf:CD1549 putative histidinol-phosphate aminotransferase.
  
 
 0.963
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.959
Ccel_1730
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
  
 
  0.933
Ccel_1965
PFAM: aminotransferase class I and II; KEGG: cno:NT01CX_0284 aspartate aminotransferase.
  
 
 0.916
Ccel_1451
PFAM: amino acid-binding ACT domain protein; KEGG: cth:Cthe_1377 hypothetical protein; Belongs to the UPF0735 family.
     
 0.905
Ccel_2880
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: cth:Cthe_1795 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase.
  
 0.888
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
  
 0.851
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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