Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rexRex DNA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (212 aa)    
Predicted Functional Partners:
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
    0.920
Ccel_2236
TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: cth:Cthe_0338 NADH-quinone oxidoreductase, E subunit.
    
 0.692
Ccel_3198
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: cdf:CD2966 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.614
Ccel_0986
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: npu:Npun_R3442 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
     
 0.538
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.475
rpsP
PFAM: ribosomal protein S16; KEGG: cth:Cthe_0769 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
    0.466
Ccel_2883
PFAM: glycosyl transferase group 1; polysaccharide pyruvyl transferase; KEGG: cth:Cthe_2702 polysaccharide pyruvyl transferase.
       0.461
Ccel_0016
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
      
 0.445
rpmG
PFAM: ribosomal protein L33; KEGG: cac:CAC3151 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
      
 0.434
argR
Arginine repressor, ArgR; Regulates arginine biosynthesis genes.
  
  
 0.428
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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