Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (235 aa)    
Predicted Functional Partners:
Ccel_2906
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 0.999
Ccel_0469
PFAM: protein of unknown function DUF214; KEGG: cth:Cthe_1761 hypothetical protein.
 
   
 0.864
Ccel_2905
PFAM: Peptidase M23; KEGG: cth:Cthe_1858 peptidase M23B.
 
   
 0.820
Ccel_2908
Transcriptional regulator, CdaR; PFAM: helix-turn-helix Fis-type; KEGG: cth:Cthe_1861 CdaR family transcriptional regulator.
       0.695
scpA
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
  
 0.575
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 
 0.553
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.505
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.504
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
   
 0.491
Ccel_2188
PFAM: NLP/P60 protein; Peptidoglycan-binding domain 1 protein; KEGG: cpy:Cphy_1886 peptidoglycan binding domain-containing protein.
  
 
 0.486
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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