Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_2986KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (804 aa)    
Predicted Functional Partners:
Ccel_2063
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.947
Ccel_0292
TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R; KEGG: cth:Cthe_1920 stage II sporulation protein R.
  
   
 0.862
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.851
Ccel_1944
TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: cth:Cthe_1328 stage II sporulation P.
  
   
 0.845
Ccel_1916
TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: cth:Cthe_0845 stage III sporulation protein spoIIIAA.
  
   
 0.829
Ccel_2061
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.824
Ccel_1910
KEGG: cth:Cthe_0839 stage III sporulation protein AG.
  
   
 0.802
Ccel_1752
TIGRFAM: stage II sporulation protein M; PFAM: protein of unknown function DUF95 transmembrane; KEGG: cth:Cthe_0675 hypothetical protein.
  
   
 0.788
Ccel_3088
TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cth:Cthe_2655 AbrB family transcriptional regulator.
 
   
 0.784
Ccel_1895
KEGG: cth:Cthe_0813 SpoIVB peptidase; TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; SMART: PDZ/DHR/GLGF domain protein.
  
   
 0.773
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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