Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_3000Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cth:Cthe_2505 LacI family transcription regulator. (346 aa)    
Predicted Functional Partners:
Ccel_0806
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: cth:Cthe_2735 HPrNtr domain-containing protein.
 
 
 
 0.702
Ccel_2999
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: bcl:ABC0314 transcriptional regulator.
 
   
0.597
Ccel_0724
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: cth:Cthe_0740 GntR family transcriptional regulator.
  
   
 0.582
Ccel_3001
PFAM: glycosidase PH1107-related; KEGG: tpt:Tpet_1543 glycosidase, PH1107-related.
 
     0.567
Ccel_2569
TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: csc:Csac_1831 pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.543
Ccel_2245
KEGG: cth:Cthe_0149 HPrNtr domain-containing protein.
   
 
 0.538
Ccel_3003
Glycosidase PH1107-related; Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose; Belongs to the glycosyl hydrolase 130 family.
 
     0.498
Ccel_1074
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: cbt:CLH_3253 transcriptional regulator.
  
   
 0.478
Ccel_3002
N-acylglucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man).
       0.467
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.456
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (22%) [HD]