| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccel_0016 | Ccel_3089 | Ccel_0016 | Ccel_3089 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | 0.491 |
| Ccel_0016 | prs | Ccel_0016 | Ccel_3092 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.503 |
| Ccel_0016 | rpoB | Ccel_0016 | Ccel_0312 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.510 |
| Ccel_1606 | Ccel_3089 | Ccel_1606 | Ccel_3089 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | 0.404 |
| Ccel_2463 | Ccel_3089 | Ccel_2463 | Ccel_3089 | PFAM: Pyrrolo-quinoline quinone; KEGG: cth:Cthe_0739 hypothetical protein. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | 0.465 |
| Ccel_3088 | Ccel_3089 | Ccel_3088 | Ccel_3089 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cth:Cthe_2655 AbrB family transcriptional regulator. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | 0.466 |
| Ccel_3088 | mfd | Ccel_3088 | Ccel_3090 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cth:Cthe_2655 AbrB family transcriptional regulator. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.578 |
| Ccel_3088 | pth | Ccel_3088 | Ccel_3091 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cth:Cthe_2655 AbrB family transcriptional regulator. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.474 |
| Ccel_3089 | Ccel_0016 | Ccel_3089 | Ccel_0016 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.491 |
| Ccel_3089 | Ccel_1606 | Ccel_3089 | Ccel_1606 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.404 |
| Ccel_3089 | Ccel_2463 | Ccel_3089 | Ccel_2463 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | PFAM: Pyrrolo-quinoline quinone; KEGG: cth:Cthe_0739 hypothetical protein. | 0.465 |
| Ccel_3089 | Ccel_3088 | Ccel_3089 | Ccel_3088 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cth:Cthe_2655 AbrB family transcriptional regulator. | 0.466 |
| Ccel_3089 | mfd | Ccel_3089 | Ccel_3090 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.585 |
| Ccel_3089 | prs | Ccel_3089 | Ccel_3092 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.435 |
| Ccel_3089 | pth | Ccel_3089 | Ccel_3091 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.550 |
| Ccel_3089 | rpoB | Ccel_3089 | Ccel_0312 | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.408 |
| mfd | Ccel_3088 | Ccel_3090 | Ccel_3088 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cth:Cthe_2655 AbrB family transcriptional regulator. | 0.578 |
| mfd | Ccel_3089 | Ccel_3090 | Ccel_3089 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cth:Cthe_2633 hypothetical protein. | 0.585 |
| mfd | prs | Ccel_3090 | Ccel_3092 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.607 |
| mfd | pth | Ccel_3090 | Ccel_3091 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.947 |