Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
Ccel_3104PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cbe:Cbei_4439 thiamine biosynthesis protein ThiH. (470 aa)    
Predicted Functional Partners:
Ccel_3103
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; KEGG: bth:BT_1837 putative GTP-binding protein, putative GTPase.
  
 0.990
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.933
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.910
Ccel_3105
KEGG: cbe:Cbei_4440 hypothetical protein.
 
     0.906
Ccel_0398
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cth:Cthe_2898 anti-sigma-factor antagonist.
  
    0.840
Ccel_2054
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.835
Ccel_3361
KEGG: cth:Cthe_2166 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
   
    0.835
Ccel_2467
TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; hydrogenase large subunit domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cth:Cthe_0342 hydrogenase, Fe-only.
 
   
 0.747
Ccel_2232
TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; hydrogenase large subunit domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cth:Cthe_0342 hydrogenase, Fe-only.
 
   
 0.740
Ccel_3099
KEGG: cth:Cthe_2622 hypothetical protein.
  
    0.682
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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