Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3116PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: cbe:Cbei_4580 two component transcriptional regulator, LytTR family. (235 aa)    
Predicted Functional Partners:
Ccel_3248
Putative sensor with HAMP domain; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase internal region; KEGG: csc:Csac_0125 histidine kinase internal region.
 
 
 0.850
Ccel_3117
KEGG: cth:Cthe_1311 signal transduction histidine kinase regulating citrate/malate metabolism.
 
  
 0.826
Ccel_1250
Signal transduction histidine kinase, LytS; PFAM: histidine kinase HAMP region domain protein; histidine kinase internal region; KEGG: hypothetical protein.
 
 
 0.818
Ccel_0994
Putative sensor with HAMP domain; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase internal region; KEGG: cbe:Cbei_4458 histidine kinase internal region.
 
  
 0.794
Ccel_1646
Putative sensor with HAMP domain; PFAM: histidine kinase HAMP region domain protein; histidine kinase internal region; KEGG: csc:Csac_2551 integral membrane sensor signal transduction histidine kinase.
 
  
 0.791
Ccel_0199
Putative sensor with HAMP domain; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase internal region; KEGG: cbe:Cbei_4963 integral membrane sensor signal transduction histidine kinase.
 
  
 0.787
Ccel_0945
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; KEGG: cbe:Cbei_4677 integral membrane sensor signal transduction histidine kinase.
 
  
 0.787
Ccel_1137
Putative sensor with HAMP domain; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase internal region; KEGG: cbe:Cbei_4677 integral membrane sensor signal transduction histidine kinase.
 
  
 0.787
Ccel_0148
Putative sensor with HAMP domain; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase internal region; KEGG: csc:Csac_2691 integral membrane sensor signal transduction histidine kinase.
 
  
 0.779
Ccel_1983
Putative sensor with HAMP domain; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase internal region; KEGG: cbe:Cbei_4458 histidine kinase internal region.
 
  
 0.778
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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