Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_3185PFAM: aminotransferase class I and II; KEGG: cpy:Cphy_0455 aminotransferase class I and II. (391 aa)    
Predicted Functional Partners:
Ccel_3186
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cpy:Cphy_0011 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.954
Ccel_2474
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: ckl:CKL_1762 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
    
 0.942
Ccel_3332
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: cth:Cthe_1842 O-acetylhomoserine/O-acetylserine sulfhydrylase.
   
 0.923
Ccel_1962
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: cbt:CLH_0332 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein.
   
 0.922
Ccel_0413
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ypm:YP_3381 pyridoxal-phosphate dependent protein.
    
 0.918
Ccel_1965
PFAM: aminotransferase class I and II; KEGG: cno:NT01CX_0284 aspartate aminotransferase.
    
0.910
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.900
Ccel_3187
PFAM: DNA/pantothenate metabolism flavoprotein domain protein; KEGG: efa:EF2655 phosphopantothenate--cysteine ligase.
    
  0.854
Ccel_1452
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: cth:Cthe_1376 homoserine dehydrogenase.
    
 0.808
gshA
PFAM: glutamate--cysteine ligase; KEGG: cac:CAC1539 gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.800
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.