Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3187PFAM: DNA/pantothenate metabolism flavoprotein domain protein; KEGG: efa:EF2655 phosphopantothenate--cysteine ligase. (264 aa)    
Predicted Functional Partners:
Ccel_3188
PFAM: flavoprotein; KEGG: efa:EF2656 phosphopantothenoylcysteine decarboxylase.
 
  
  0.985
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
    
 0.914
Ccel_0705
KEGG: pdi:BDI_2301 pantothenate kinase.
     
 0.908
Ccel_3186
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cpy:Cphy_0011 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.891
Ccel_3185
PFAM: aminotransferase class I and II; KEGG: cpy:Cphy_0455 aminotransferase class I and II.
    
  0.854
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.843
Ccel_1965
PFAM: aminotransferase class I and II; KEGG: cno:NT01CX_0284 aspartate aminotransferase.
  
  0.832
Ccel_0413
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ypm:YP_3381 pyridoxal-phosphate dependent protein.
    
 0.808
Ccel_0177
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
  
 0.634
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
  
 0.612
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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