Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3189PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cpy:Cphy_2083 biotin synthase. (345 aa)    
Predicted Functional Partners:
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.963
Ccel_3103
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; KEGG: bth:BT_1837 putative GTP-binding protein, putative GTPase.
   
 0.942
Ccel_3259
PFAM: aminotransferase class-III; KEGG: bca:BCE_4189 adenosylmethionine--8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.918
Ccel_2467
TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; hydrogenase large subunit domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cth:Cthe_0342 hydrogenase, Fe-only.
 
  
 0.850
Ccel_2232
TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; hydrogenase large subunit domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cth:Cthe_0342 hydrogenase, Fe-only.
 
  
 0.847
Ccel_3105
KEGG: cbe:Cbei_4440 hypothetical protein.
 
    0.807
Ccel_2303
TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; hydrogenase large subunit domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: aoe:Clos_0990 hydrogenase, Fe-only.
 
  
 0.700
Ccel_3104
PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cbe:Cbei_4439 thiamine biosynthesis protein ThiH.
 
  
0.667
Ccel_3187
PFAM: DNA/pantothenate metabolism flavoprotein domain protein; KEGG: efa:EF2655 phosphopantothenate--cysteine ligase.
  
  
 0.611
Ccel_3188
PFAM: flavoprotein; KEGG: efa:EF2656 phosphopantothenoylcysteine decarboxylase.
  
  
 0.611
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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