Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3259PFAM: aminotransferase class-III; KEGG: bca:BCE_4189 adenosylmethionine--8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)    
Predicted Functional Partners:
Ccel_3189
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cpy:Cphy_2083 biotin synthase.
  
  
 0.918
Ccel_3260
PFAM: protein of unknown function DUF98; KEGG: btl:BALH_2115 hypothetical protein.
       0.640
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.629
Ccel_2331
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; KEGG: bsu:BSU17180 polyketide synthase of type I.
  
  
 0.622
Ccel_3257
KEGG: saq:Sare_0485 hypothetical protein.
  
  
 0.612
Ccel_3255
PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: gme:Gmet_2019 Orn/DAP/Arg decarboxylase 2.
 
   
 0.596
Ccel_3258
KEGG: dde:Dde_1603 hypothetical protein.
  
    0.594
Ccel_0528
TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: cth:Cthe_1375 aspartate kinase; Belongs to the aspartokinase family.
    
 0.576
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
   
 0.555
Ccel_2378
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; KEGG: bld:BLi00401 lichenysin synthetase A.
  
  
 0.525
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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