STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_3264Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: cdf:CD1883 AraC family transcription regulator. (287 aa)    
Predicted Functional Partners:
Ccel_3263
PFAM: transcription activator effector binding; KEGG: cdf:CD1605 hypothetical protein.
 
     0.889
Ccel_3261
PFAM: ABC-2 type transporter; KEGG: cdf:CD1603 ABC transporter, permease protein.
 
     0.873
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.848
Ccel_3262
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cdf:CD1604 ABC transporter, ATP-binding protein.
 
     0.776
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.738
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.723
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.707
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.707
Ccel_2638
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; transcription activator effector binding; KEGG: cbb:CLD_2330 MerR family transcriptional regulator.
 
   
 0.610
Ccel_2672
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: cdf:CD1725 AraC family transcription regulator.
  
     0.602
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.