Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3310PFAM: SMC domain protein; KEGG: spj:MGAS2096_Spy0560 chromosome segregation ATPases. (433 aa)    
Predicted Functional Partners:
Ccel_3309
Phage protein; KEGG: spj:MGAS2096_Spy0561 phage protein.
 
    0.958
Ccel_3307
PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: spj:MGAS2096_Spy0565 DNA/RNA helicase.
 
  
 0.946
Ccel_3308
Phage protein; KEGG: spj:MGAS2096_Spy0564 phage protein.
 
     0.943
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.925
Ccel_3304
PFAM: Primase 2; KEGG: spj:MGAS2096_Spy0567 ATPase.
 
     0.925
Ccel_3302
PFAM: endodeoxyribonuclease RusA; KEGG: spj:MGAS2096_Spy0569 phage protein.
 
     0.843
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
 0.828
Ccel_0031
PFAM: metallophosphoesterase; KEGG: cth:Cthe_2411 metallophosphoesterase.
  
 0.798
Ccel_3306
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sha:SH2634 hypothetical protein; Belongs to the ParB family.
 
     0.689
Ccel_3305
KEGG: bce:BC1869 phage protein.
  
    0.647
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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