Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Ccel_3329PFAM: helix-hairpin-helix motif; 8-oxoguanine DNA glycosylase domain protein; SMART: HhH-GPD family protein; KEGG: cth:Cthe_2068 8-oxoguanine DNA glycosylase-like protein. (295 aa)    
Predicted Functional Partners:
Ccel_3322
TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cth:Cthe_0458 exodeoxyribonuclease III Xth.
   
 0.728
Ccel_3341
KEGG: cth:Cthe_2072 hypothetical protein.
  
     0.694
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.643
Ccel_1326
KEGG: cth:Cthe_0165 hypothetical protein.
  
     0.615
Ccel_1925
PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2; KEGG: tpd:Teth39_1081 xylose isomerase domain-containing protein.
    
 
 0.599
Ccel_0041
PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC.
  
     0.593
Ccel_3330
KEGG: cth:Cthe_2069 hypothetical protein.
       0.569
dinB
UMUC domain protein DNA-repair protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.547
dinB-2
UMUC domain protein DNA-repair protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.547
Ccel_0042
TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD.
  
     0.534
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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